Le séminaire “Strategies for antifungal development: hit to lead against new molecular targets” de la professeure Maria Sueli Felipe de l’Université de Brasilia, organisé par l’équipe Capsid, aura lieu mardi 24 octobre à 14 h en salle A008.

Résumé sur la professeure Maria Sueli Felipe :

Maria Sueli Felipe has chemistry and molecular biology/biochemistry experience since 70-80`decades. She is an Emeritus professor at Brasilia University, now is professor at Catholic University of Brasilia, and Senior Research at CNPq. I have been working with human fungal pathogens, specially the neglected tropical fungi, for about 30 years, coordinating projects about fungal genome, host-pathogen interaction, and post-genomic data aiming developing new antifungal compounds against new targets identified by comparative genomics. Trr1 (Thioredoxin Reductase) enzyme is one of those targets, and for about 10 years now we started a collaboration with Loria (Bernard Maigret). I will talk about the timeline and development of new potential compounds with antifungal activities, future trends and perspectives of this relevant topic, considering the scarce arsenal and resistance for human fungal infections, including tropical neglected diseases.