Workshop at the Computational Neuroscience Conference CNS 2013 in Paris

Organizer : Axel Hutt, INRIA Nancy

When : Thursday July 18, 2013

Modeling general anesthesia: from theory to experiments

The neural dynamics during general anesthesia is far from being understood. One reason for this lack of understanding is the complex neural interactions
on different spatial and temporal scales. For instance, anesthetic agents act on synaptic receptors essentially evoking a macroscopic change of population
activity, such as Local Field Potentials, EEG/MEG or resulting change of cerebral blood flow, and inducing the loss of consciousness in patients.
The workshop aims to address recent theoretical and experimental advances in the field and provides a forum for an improved exchange of ideas between
different research groups.

Tentative time schedule (talks of 30 minutes questions included):

Welcome by Axel Hutt, INRIA Nancy

9:00 - 9:30

Jamie Sleigh, University of Auckland :
An explanation for the variation in trajectories during emergence from general anaesthesia

9:30 - 10:00

Alain Destexhe, CNRS Paris:
Excitatory and inhibitory cell activity in human temporal cortex during wake and sleep states

10:00 - 10:30

Kristin Sellers, University of North Carolina - Chapel Hill:
Anesthesia amplifies visual responses through cortical disconnectivity and suppression of spontaneous state dynamics

10:30 - 11:00


11:00 - 11:30

Anthony Hudetz, Medical College of Wisconsin:
Anesthesia shrinks the repertoire of brain states as estimated from electrophysiological and fMRI data

11:30 - 12:00

Alistair Steyn-Ross, University of Wakato:
Investigation of inhibitory mechanisms in a mean-field anaesthesia model

12:00 - 12:30

UnCheol Lee, University of Michigan:
The inhibition of feedback connectivity after anesthetic induced unconsciousness associates with reconfiguration of brain network hub structure: study with empirical EEG data and mathematical modeling.

12:30 - 14:30


14:30 - 15:00

Rosalyn Moran, Virginia Tech Carilion Research Institute:
Dynamic Causal Modelling Assessments of Propofol and Ketamine induced connectivity changes

15:00 - 15:30

Lennaert van Veen, University of Ontario:
Mean field modelling of burst suppression in general anaesthesia

15:30 - 16:00

Axel Hutt, INRIA Nancy :
Alpha-power increase in frontal EEG-electrodes during anaesthesia : insights from neural mass models